Revison 1
Here's a simple JavaScript solution to hide your e-mail from many spam scripts while still providing clickable hyperlinks to your visitors.

Web crawlers and visitors with JavaScript disabled will see: me [at] mydomain [dot] com. I've seen a lot of people that just leave it at this, but it seems a bit unprofessional in my opinion. With the following code, we can replace that with a fully functional hyperlink.